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. 2006 Mar 14;66(5):727-9.
doi: 10.1212/01.wnl.0000200777.96896.3d. Epub 2006 Jan 25.

Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study

J A Frontera  1 , T Rundek, J M Schmidt, J Claassen, A Parra, K E Wartenberg, R E Temes, S A Mayer, J P Mohr, R S Marshall
Affiliations

Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study

J A Frontera et al. Neurology. .

Abstract

The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2R and in none of 6 patients with preserved reactivity (p = 0.011). Abnormal CO2R preceded the onset of vasospasm in 7 of 9 patients. Abnormal standard TCD testing was not associated with vasospasm.

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