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. 2006 Feb;50(2):756-8.
doi: 10.1128/AAC.50.2.756-758.2006.

Occurrence of OXA-58-like carbapenemases in Acinetobacter spp. collected over 10 years in three continents

Juliana Coelho  1 , Neil Woodford, Mariya Afzal-Shah, David Livermore
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Occurrence of OXA-58-like carbapenemases in Acinetobacter spp. collected over 10 years in three continents

Juliana Coelho et al. Antimicrob Agents Chemother. 2006 Feb.

Abstract

OXA-58 is a recently described carbapenemase from Acinetobacter spp. in Europe. We examined earlier worldwide Acinetobacter collections and found bla(OXA-58) in 30 carbapenem-nonsusceptible isolates, including several isolates collected in Argentina and Kuwait in 1995 and 1996 and in a British outbreak strain from 2000. Most isolates (28 of 30) also had bla(OXA-51). We conclude that bla(OXA-58) is geographically widespread and has occurred in Acinetobacter spp. for over 10 years.

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Figures

FIG. 1.
FIG. 1.
Characteristics and sources of Acinetobacter sp. isolates with blaOXA-58. Clonal isolates from the cluster of 15 isolates collected at a British hospital in 2000 are shaded light gray; those collected from the hospital in Argentina in 1995 and 1996 are shaded dark gray. “UK referred” means referred to the national reference laboratory from diagnostic laboratories within the United Kingdom. IPM, imipenem; MEM, meropenem.
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