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. 2006 Feb;6(2):67-9.
doi: 10.1016/S1473-3099(06)70361-9.

New insights into the antiviral effects of chloroquine

Andrea Savarino, Livia Di Trani, Isabella Donatelli, Roberto Cauda, Antonio Cassone

New insights into the antiviral effects of chloroquine

Andrea Savarino et al. Lancet Infect Dis. 2006 Feb.
No abstract available

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Figures

Figure
Figure
Can chloroquine interact with sugar-modifying enzymes? This computer-assisted simulation of ligand/protein docking by use of the program GOLD indicates that chloroquine (red) fits to the active site of UDP-N-acetylglucosamine 2-epimerase (grey). This evidence suggests that chloroquine could inhibit the enzyme that catalyses the rate-determining step in the sialic acid biosynthetic pathway.
See this image and copyright information in PMC

References

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