Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 May;92(1):35-44.
doi: 10.1016/j.jad.2005.12.034. Epub 2006 Jan 26.

Can personality assessment predict future depression? A twelve-month follow-up of 631 subjects

Affiliations

Can personality assessment predict future depression? A twelve-month follow-up of 631 subjects

C Robert Cloninger et al. J Affect Disord. 2006 May.

Abstract

Background: Personality assessment provides a description of a person's fundamental emotional needs and of the higher cognitive processes that modulate thoughts, feelings, and behavior. Prior studies by us examined personality and mood at the same time. Assessing personality may allow prediction of mood changes over time in a longitudinal study, as described in earlier prospective studies by Paula Clayton and others.

Method: A group of 631 adults representative of the general population completed the Temperament and Character Inventory (TCI) and Center for Epidemiological Studies depression scale (CES-D) at baseline and one year later.

Results: TCI scores at baseline accounted for gender differences in levels of depression. TCI personality scores were strongly stable (range in r=.78 to .85 for each of seven dimensions) whereas mood was only moderately stable (r=.62) over the twelve-month follow-up. Baseline personality scores (particularly high Harm Avoidance and low Self-Directedness) explained 44% of the variance in the change in depression. Baseline levels and changes in Harm Avoidance and Self-Directedness explained 52% of the variance in the change in depression at follow-up.

Limitations: The follow-up sample was representative of the target population except for slightly lower Novelty Seeking scores.

Clinical relevance: Observable personality levels strongly predict mood changes. Personality development may reduce vulnerability to future depression.

PubMed Disclaimer

Similar articles

Cited by

LinkOut - more resources