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. 2006 Feb;255(2):240-6.
doi: 10.1111/j.1574-6968.2005.00076.x.

Osmotic stress responses of Streptococcus mutans UA159

Jacqueline Abranches  1 , José A Lemos, Robert A Burne
Affiliations

Osmotic stress responses of Streptococcus mutans UA159

Jacqueline Abranches et al. FEMS Microbiol Lett. 2006 Feb.

Abstract

The hyperosmotic stress response of Streptococcus mutans was investigated. Real-time reverse transcriptase-PCR and slot-blot analysis revealed that opuAA, opcA, Smu.2115, sodA and nox were induced after exposure to 0.4 M NaCl. Our data suggest that there is a cross-talk between osmotic and oxidative stress responses in S. mutans. Inactivation of Smu.2115, encoding a putative oxidoreductase, resulted in an acid-resistant and hydrogen peroxide-sensitive phenotype.

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