Review
doi: 10.1080/08035250500301133.
Influence of early postnatal nutritional management on oxidative stress and antioxidant defence in extreme prematurity
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- PMID: 16449020
- DOI: 10.1080/08035250500301133
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Review
Influence of early postnatal nutritional management on oxidative stress and antioxidant defence in extreme prematurity
Acta Paediatr.
2006 Feb.
Abstract
The increased survival of infants born at mid-gestation in the last decade is associated with significant oxygen free radical-mediated morbidities. Resuscitation with 100% oxygen, oxidant load from parenteral nutrition fluids, and oxidant stress inherent to the systemic inflammatory state subsequent to infection and tissue injury are all contributory.
Conclusion: Improving early postnatal protein nutrition and the formulation of parenteral nutrition fluids would potentially reduce the oxidative stress and enhance the antioxidant defence of extremely premature newborns.
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