Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14
- PMID: 16451628
- PMCID: PMC1866767
- DOI: 10.1186/1471-2156-6-S1-S2
Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14
Abstract
The data provided to the Genetic Analysis Workshop 14 (GAW 14) was the result of a collaboration among several different groups, catalyzed by Elizabeth Pugh from The Center for Inherited Disease Research (CIDR) and the organizers of GAW 14, Jean MacCluer and Laura Almasy. The DNA, phenotypic characterization, and microsatellite genomic survey were provided by the Collaborative Study on the Genetics of Alcoholism (COGA), a nine-site national collaboration funded by the National Institute of Alcohol and Alcoholism (NIAAA) and the National Institute of Drug Abuse (NIDA) with the overarching goal of identifying and characterizing genes that affect the susceptibility to develop alcohol dependence and related phenotypes. CIDR, Affymetrix, and Illumina provided single-nucleotide polymorphism genotyping of a large subset of the COGA subjects. This article briefly describes the dataset that was provided.
Figures
Similar articles
-
Characteristics of replicated single-nucleotide polymorphism genotypes from COGA: Affymetrix and Center for Inherited Disease Research.BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S154. doi: 10.1186/1471-2156-6-S1-S154. BMC Genet. 2005. PMID: 16451615 Free PMC article.
-
A genome-wide linkage analysis of alcoholism on microsatellite and single-nucleotide polymorphism data, using alcohol dependence phenotypes and electroencephalogram measures.BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S17. doi: 10.1186/1471-2156-6-S1-S17. BMC Genet. 2005. PMID: 16451625 Free PMC article.
-
Microsatellite linkage analysis, single-nucleotide polymorphisms, and haplotype associations with ECB21 in the COGA data.BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S94. doi: 10.1186/1471-2156-6-S1-S94. BMC Genet. 2005. PMID: 16451710 Free PMC article.
-
The collaborative study on the genetics of alcoholism: Sample and clinical data.Genes Brain Behav. 2023 Oct;22(5):e12860. doi: 10.1111/gbb.12860. Epub 2023 Aug 15. Genes Brain Behav. 2023. PMID: 37581339 Free PMC article. Review.
-
The genetics of alcoholism: identifying specific genes through family studies.Addict Biol. 2006 Sep;11(3-4):386-96. doi: 10.1111/j.1369-1600.2006.00035.x. Addict Biol. 2006. PMID: 16961766 Review.
Cited by
-
XM: association testing on the X-chromosome in case-control samples with related individuals.Genet Epidemiol. 2012 Jul;36(5):438-50. doi: 10.1002/gepi.21638. Epub 2012 May 2. Genet Epidemiol. 2012. PMID: 22552845 Free PMC article.
-
Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study.J Neural Transm (Vienna). 2011 Sep;118(9):1293-9. doi: 10.1007/s00702-011-0628-3. Epub 2011 Mar 29. J Neural Transm (Vienna). 2011. PMID: 21445666
-
A KCNJ6 gene polymorphism modulates theta oscillations during reward processing.Int J Psychophysiol. 2017 May;115:13-23. doi: 10.1016/j.ijpsycho.2016.12.007. Epub 2016 Dec 16. Int J Psychophysiol. 2017. PMID: 27993610 Free PMC article.
-
FaST linear mixed models for genome-wide association studies.Nat Methods. 2011 Sep 4;8(10):833-5. doi: 10.1038/nmeth.1681. Nat Methods. 2011. PMID: 21892150
-
Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain.Front Neurosci. 2011 Oct 19;5:120. doi: 10.3389/fnins.2011.00120. eCollection 2011. Front Neurosci. 2011. PMID: 22028680 Free PMC article.
References
-
- Begleiter H, Reich T, Nurnberger J, Jr, Li TK, Conneally PM, Edenberg H, Crowe R, Kuperman S, Schuckit M, Bloom F, Hesselbrock V, Porjesz B, Cloninger CR, Rice J, Goate A. Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genet Epidemiol. 1999;17:S25–S30. - PubMed
-
- Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li TK, Conneally PM, Nurnberger JI, Jr, Tischfield JA, Crowe RR, Cloninger CR, Wu W, Shears S, Carr K, Crose C, Willig C, Begleiter H. Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet. 1998;81:207–215. doi: 10.1002/(SICI)1096-8628(19980508)81:3<207::AID-AJMG1>3.0.CO;2-T. - DOI - PubMed
-
- Begleiter H, Porjesz B, Reich T, Edenberg HJ, Goate A, Blangero J, Almasy L, Foroud T, Van Eerdewegh P, Polich J, Rohrbaugh J, Kuperman S, Bauer LO, O'Connor SJ, Chorlian DB, Li TK, Conneally PM, Hesselbrock V, Rice JP, Schuckit MA, Cloninger R, Nurnberger J, Jr, Crowe R, Bloom FE. Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalogr Clin Neurophysiol. 1998;108:244–250. doi: 10.1016/S0168-5597(98)00002-1. - DOI - PubMed
-
- Almasy L, Porjesz B, Blangero J, Goate A, Edenberg HJ, Chorlian DB, Kuperman S, O'Connor SJ, Rohrbaugh J, Bauer LO, Foroud T, Rice JP, Reich T, Begleiter H. Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. Am J Hum Genet. 2001;68:128–135. doi: 10.1086/316936. - DOI - PMC - PubMed
-
- Foroud T, Edenberg HJ, Goate A, Rice J, Flury L, Koller DL, Bierut LJ, Conneally PM, Nurnberger JI, Bucholz KK, Li TK, Hesselbrock V, Crowe R, Schuckit M, Porjesz B, Begleiter H, Reich T. Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. Alcohol Clin Exp Res. 24:933–945. doi: 10.1111/j.1530-0277.2000.tb04634.x. - DOI - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Molecular Biology Databases