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. 2005 Dec 30;6 Suppl 1(Suppl 1):S2.
doi: 10.1186/1471-2156-6-S1-S2.

Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14

Howard J Edenberg  1 , Laura J Bierut, Paul Boyce, Manqiu Cao, Simon Cawley, Richard Chiles, Kimberly F Doheny, Mark Hansen, Tony Hinrichs, Kevin Jones, Mark Kelleher, Giulia C Kennedy, Guoying Liu, Gregory Marcus, Celeste McBride, Sarah Shaw Murray, Arnold Oliphant, James Pettengill, Bernice Porjesz, Elizabeth W Pugh, John P Rice, Todd Rubano, Stu Shannon, Rhoberta Steeke, Jay A Tischfield, Ya Yu Tsai, Chun Zhang, Henri Begleiter
Affiliations

Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14

Howard J Edenberg et al. BMC Genet. .

Abstract

The data provided to the Genetic Analysis Workshop 14 (GAW 14) was the result of a collaboration among several different groups, catalyzed by Elizabeth Pugh from The Center for Inherited Disease Research (CIDR) and the organizers of GAW 14, Jean MacCluer and Laura Almasy. The DNA, phenotypic characterization, and microsatellite genomic survey were provided by the Collaborative Study on the Genetics of Alcoholism (COGA), a nine-site national collaboration funded by the National Institute of Alcohol and Alcoholism (NIAAA) and the National Institute of Drug Abuse (NIDA) with the overarching goal of identifying and characterizing genes that affect the susceptibility to develop alcohol dependence and related phenotypes. CIDR, Affymetrix, and Illumina provided single-nucleotide polymorphism genotyping of a large subset of the COGA subjects. This article briefly describes the dataset that was provided.

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Figures

Figure 1
Figure 1
COGA data subset for GAW 14. The GAW 14 dataset was drawn partly from Wave 1 and partly from Wave 2.
See this image and copyright information in PMC

References

    1. Begleiter H, Reich T, Nurnberger J, Jr, Li TK, Conneally PM, Edenberg H, Crowe R, Kuperman S, Schuckit M, Bloom F, Hesselbrock V, Porjesz B, Cloninger CR, Rice J, Goate A. Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genet Epidemiol. 1999;17:S25–S30. - PubMed
    1. Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li TK, Conneally PM, Nurnberger JI, Jr, Tischfield JA, Crowe RR, Cloninger CR, Wu W, Shears S, Carr K, Crose C, Willig C, Begleiter H. Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet. 1998;81:207–215. doi: 10.1002/(SICI)1096-8628(19980508)81:3<207::AID-AJMG1>3.0.CO;2-T. - DOI - PubMed
    1. Begleiter H, Porjesz B, Reich T, Edenberg HJ, Goate A, Blangero J, Almasy L, Foroud T, Van Eerdewegh P, Polich J, Rohrbaugh J, Kuperman S, Bauer LO, O'Connor SJ, Chorlian DB, Li TK, Conneally PM, Hesselbrock V, Rice JP, Schuckit MA, Cloninger R, Nurnberger J, Jr, Crowe R, Bloom FE. Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalogr Clin Neurophysiol. 1998;108:244–250. doi: 10.1016/S0168-5597(98)00002-1. - DOI - PubMed
    1. Almasy L, Porjesz B, Blangero J, Goate A, Edenberg HJ, Chorlian DB, Kuperman S, O'Connor SJ, Rohrbaugh J, Bauer LO, Foroud T, Rice JP, Reich T, Begleiter H. Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. Am J Hum Genet. 2001;68:128–135. doi: 10.1086/316936. - DOI - PMC - PubMed
    1. Foroud T, Edenberg HJ, Goate A, Rice J, Flury L, Koller DL, Bierut LJ, Conneally PM, Nurnberger JI, Bucholz KK, Li TK, Hesselbrock V, Crowe R, Schuckit M, Porjesz B, Begleiter H, Reich T. Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. Alcohol Clin Exp Res. 24:933–945. doi: 10.1111/j.1530-0277.2000.tb04634.x. - DOI - PubMed

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