Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983;2(5):751-5.
doi: 10.1002/j.1460-2075.1983.tb01495.x.

Structural homology between different archaebacterial DNA-dependent RNA polymerases analyzed by immunological comparison of their components

R Schnabel  1 , M Thomm, R Gerardy-Schahn, W Zillig, K O Stetter, J Huet
Affiliations

Structural homology between different archaebacterial DNA-dependent RNA polymerases analyzed by immunological comparison of their components

R Schnabel et al. EMBO J. 1983.

Abstract

The archaebacterial DNA-dependent RNA polymerases have a complex structure containing eight or more components. Immunochemical analysis shows an extensive homology between the components of the enzymes of nine different species. Two enzyme subtypes can be distinguished: that of the thermoacidophilic and/or sulfur-metabolizing archaebacteria with the composition BACDEFGHIJ and that of the methanogenic plus halophilic archaebacteria with the composition ABB'C(D).... Components B and B' of the latter subtype probably evolved by the division of the large component B of the BACD... type enzyme. The existence of the two subtypes corroborates the division of the archaebacteria into two phylogenetic main branches.

PubMed Disclaimer

References

    1. Eur J Biochem. 1979 Jun 1;96(3):597-604 - PubMed
    1. Hoppe Seylers Z Physiol Chem. 1977 Sep;358(9):1093-104 - PubMed
    1. J Biol Chem. 1982 Mar 10;257(5):2613-8 - PubMed
    1. Science. 1980 Jul 25;209(4455):457-63 - PubMed
    1. Proc Natl Acad Sci U S A. 1979 Sep;76(9):4350-4 - PubMed