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Multicenter Study
. 2006 Feb;44(2):614-6.
doi: 10.1128/JCM.44.2.614-616.2006.

Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies

Syria Laperche  1 , Karine Saune, Paul Dény, Gilles Duverlie, Sophie Alain, Marie-Laure Chaix, Catherine Gaudy, Françoise Lunel, Jean-Michel Pawlotsky, Christopher Payan, Bruno Pozzetto, Catherine Tamalet, Vincent Thibault, Sophie Vallet, Françoise Bouchardeau, Jacques Izopet, Jean-Jacques Lefrère
Affiliations
Multicenter Study

Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies

Syria Laperche et al. J Clin Microbiol. 2006 Feb.

Abstract

A multicenter study of NS5b hepatitis C virus (HCV) genotype determination involving 12 laboratories demonstrates that any laboratory with expertise in sequencing techniques would be able to provide a reliable HCV genotype for clinical and epidemiological purposes as long as they are provided a consensus reference sequence database.

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