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. 2006 Feb;44(2):628-31.
doi: 10.1128/JCM.44.2.628-631.2006.

Sonication of explanted prosthetic components in bags for diagnosis of prosthetic joint infection is associated with risk of contamination

Andrej Trampuz  1 , Kerryl E Piper, Arlen D Hanssen, Douglas R Osmon, Franklin R Cockerill, James M Steckelberg, Robin Patel
Affiliations

Sonication of explanted prosthetic components in bags for diagnosis of prosthetic joint infection is associated with risk of contamination

Andrej Trampuz et al. J Clin Microbiol. 2006 Feb.

Abstract

Explanted orthopedic implants from 54 patients with aseptic failure and 24 patients with prosthetic knee or hip infection were sonicated in polyethylene bags. The sensitivities of periprosthetic tissue and sonicate fluid cultures for the diagnosis of prosthetic joint infection were 54% and 75%, whereas the specificities were 98% and 87%, respectively. Sonication in bags improved bacterial recovery from the surface of orthopedic implants; however, it lacked specificity, due to bag leakage.

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References

    1. Berbari, E. F., A. D. Hanssen, M. C. Duffy, J. M. Steckelberg, D. M. Ilstrup, W. S. Harmsen, and D. R. Osmon. 1998. Risk factors of prosthetic joint infection: case-control study. Clin. Infect. Dis. 27:1247-1254. - PubMed
    1. Donlan, R. M. 2001. Biofilm formation: a clinically relevant microbiological process. Clin. Infect. Dis. 33:1387-1392. - PubMed
    1. Hughes, J. G., E. A. Vetter, R. Patel, C. D. Schleck, S. Harmsen, L. T. Turgeant, and F. R. Cockerill III. 2001. Culture with BACTEC Peds Plus/F bottle compared with conventional methods for detection of bacteria in synovial fluid. J. Clin. Microbiol. 39:4468-4471. - PMC - PubMed
    1. Nguyen, L. L., C. L. Nelson, M. Saccente, M. S. Smeltzer, D. L. Wassell, and S. G. McLaren. 2002. Detecting bacterial colonization of implanted orthopaedic devices by ultrasonication. Clin. Orthop. Relat. Res. 403:29-37. - PubMed
    1. Rand, J. A., and D. M. Ilstrup. 1991. Survivorship analysis of total knee arthroplasty. Cumulative rates of survival of 9200 total knee arthroplasties. J. Bone Jt. Surg. Am. Vol. 73:397-409. - PubMed

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