A role for neurotrophins in embryonic stem cell growth
- PMID: 16459295
- DOI: 10.1016/j.devcel.2006.01.007
A role for neurotrophins in embryonic stem cell growth
Abstract
Neurotrophins act on embryonic cells through TRK receptors to inhibit apoptosis by phosphorylation of AKT. In a recent paper in Nature Biotechnology, show that the presence of selected neurotrophins enables cloning of trypsinized single embryonic stem cells and potentially increases the availability and usefulness of these stem cells.
Comment on
-
Neurotrophins mediate human embryonic stem cell survival.Nat Biotechnol. 2006 Mar;24(3):344-50. doi: 10.1038/nbt1189. Epub 2006 Jan 29. Nat Biotechnol. 2006. PMID: 16444268
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources