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Comment
. 2006 Feb;10(2):158-9.
doi: 10.1016/j.devcel.2006.01.007.

A role for neurotrophins in embryonic stem cell growth

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A role for neurotrophins in embryonic stem cell growth

Alan Trounson et al. Dev Cell. 2006 Feb.
Free article

Abstract

Neurotrophins act on embryonic cells through TRK receptors to inhibit apoptosis by phosphorylation of AKT. In a recent paper in Nature Biotechnology, show that the presence of selected neurotrophins enables cloning of trypsinized single embryonic stem cells and potentially increases the availability and usefulness of these stem cells.

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