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Review
. 2006 Jan;88(1):3-8.
doi: 10.1308/003588406X83104.

Management of Dupuytren's disease--clear advice for an elusive condition

A Bayat  1 , D A McGrouther
Affiliations
Review

Management of Dupuytren's disease--clear advice for an elusive condition

A Bayat et al. Ann R Coll Surg Engl. 2006 Jan.

Abstract

Dupuytren's disease is a progressive fibroproliferative disorder of an unknown origin affecting the hands causing permanent flexion contracture of the digits. Significant risk factors for development of Dupuytren's disease include old age, male sex, white northern European extraction, presence of positive family history of Dupuytren's disease, and diabetes mellitus. The disease also seems to deteriorate rapidly in those cases showing young age of onset and additional fibromatosis affecting the back of the hands, soles of the feet and the penis. Although there is no cure, patients with Dupuytren's disease of the hand may gain a significant functional benefit following surgical improvement or correction of the deformity. With realistic expectations, timely and appropriate surgical technique in a specialist centre, and attention to postoperative recovery and rehabilitation (occupational therapy and physiotherapy support), a beneficial outcome can be achieved in most cases.

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Figures

Figure 1
Figure 1
Diagrammatic illustration of clinical presentation in Dupytren's disease; from simple nedule to thick fibrous band formation and finally to finger contracture.
Figure 2
Figure 2
Flow chart for managing patients with Dupuytren's disease from diagnosis to treatment.
See this image and copyright information in PMC

References

    1. Dupuytren BG. Permanent retraction of the fingers, produced by an affection of the palmar fascia. Lancet. 1834;ii:222–5.
    1. Burge P. Genetics of Dupuytren's disease. Hand Clin. 1999;15:63–72. - PubMed
    1. Gudmundsson KG, Arngrimsson R, Jonsson T. Eighteen year follow-up study of the clinical manifestations and progression of Dupuytren's disease. Scan J Rheumatol. 2001;30:31–4. - PubMed
    1. Leclercq C. Results of surgical treatment. In: Tubiana, et al., editors. Dupuytren's disease. 1st edn. London: Martin Dunitz; 2000. pp. 239–50.
    1. Gudmundsson KG, Arngrimsson R, Sigfusson N, Bjornsson A, Jonsson T. Epidemiology of Dupuytren's disease: clinical, serological, and social assessment. The Reykjavik Study. J Clin Epidemiol. 2000;53:291–6. - PubMed

Reading recommendations

    1. McFarlane R, McGrouther DA, Flint M, editors. Dupuytren's Disease, Biology & Treatment. Edinburgh: Churchill Livingstone; 1990.
    1. Tubiana R, Leclercq C, Hurst LC, Badalamente MA, Mackin EJ. Dupuytren's Disease. Martin Dunitz; 2000.
    1. McGrouther DA. Green DP, Hotchkiss RN, Pederson WC. Green's Operative Hand Surgery. 5th edn. Vol I. New York: Churchill Livingstone; 2004. Dupuytren's contracture.

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