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Comment
. 2006 Feb 14;103(7):2007-8.
doi: 10.1073/pnas.0600085103. Epub 2006 Feb 6.

Standing guard: Perinuclear localization of an RNA-dependent RNA polymerase

William G Kelly  1
Affiliations
Comment

Standing guard: Perinuclear localization of an RNA-dependent RNA polymerase

William G Kelly. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

Conflict of interest statement: No conflicts declared.

Figures

Fig. 1.
Fig. 1.
Model for meiotic silencing in N. crassa. Aberrant RNAs generated by inappropriate transcription of unpaired DNA during meiosis are recognized as substrates by the SAD-1 RdRP anchored near nuclear pores by SAD-2. The dsRNA synthesized by SAD-1 is cleaved by Dicer to generate siRNAs. These siRNAs are used as guides by the RISC complex to degrade RNAs with sequence homology to the siRNA.
See this image and copyright information in PMC

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