What about chemoprevention for melanoma?

Abstract

Purpose of review: This paper aims to critically review the potential for a chemoprevention strategy in melanoma, and to discuss new data on candidate chemoprevention agents, as chemoprevention has been suggested as an unexplored approach in melanoma.

Recent findings: A strong scientific rationale, established long-term safety of candidate agents, and a systematic step-wise approach to chemoprevention agent development are all critical for melanoma chemoprevention research. Among potential agents, the lipid-lowering drugs, the statins, satisfy these prerequisites.

Summary: Chemoprevention of cutaneous melanoma can become a valid strategy complementing current prevention approaches, as long as these important prerequisites are taken into consideration.