Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2006 Feb;3(2):104-7.
doi: 10.1038/ncponc0405.

Hypocalcemia associated with bone metastases in a patient with salivary-gland carcinoma

Sarah-Jane Dawson  1 , Robin M L Murray, Danny Rischin
Affiliations
Case Reports

Hypocalcemia associated with bone metastases in a patient with salivary-gland carcinoma

Sarah-Jane Dawson et al. Nat Clin Pract Oncol. 2006 Feb.

Abstract

Background: A 70-year-old man presented with a smooth lump on his buccal mucosa and right-sided cervical lymphadenopathy. Staging investigations revealed extensive sclerotic bone metastases and the patient subsequently underwent palliative radiotherapy to the right face and cervical region. Seven months later he presented with a 4-day history of fatigue, muscle cramps, ataxia, paraesthesia, and blurred vision.

Investigations: Physical examination, biopsy of abnormal buccal mucosa, routine biochemistry, electrocardiogram, bone scan, CT scans of the chest, abdomen and pelvis, and MRI of the brain.

Diagnosis: Undifferentiated carcinoma of the salivary gland with sclerotic bone metastases and hypocalcemia.

Management: Palliative radiotherapy to the right face and cervical region, infusions of calcium gluconate and calcium chloride, oral calcium carbonate, vitamin D and magnesium, palliative chemotherapy (carboplatin and 5-fluorouracil), and whole brain radiotherapy.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • Engineering models of head and neck and oral cancers on-a-chip.
    da Costa Sousa MG, Vignolo SM, Franca CM, Mereness J, Alves Fraga MA, Silva-Sousa AC, Benoit DSW, Bertassoni LE. da Costa Sousa MG, et al. Biomicrofluidics. 2024 Mar 6;18(2):021502. doi: 10.1063/5.0186722. eCollection 2024 Mar. Biomicrofluidics. 2024. PMID: 38464668 Free PMC article. Review.
  • Clinical features of brain metastasis from salivary gland tumors.
    Venteicher AS, Walcott BP, Sheth SA, Snuderl M, Patel AP, Curry WT, Nahed BV. Venteicher AS, et al. J Clin Neurosci. 2013 Nov;20(11):1533-7. doi: 10.1016/j.jocn.2012.11.024. Epub 2013 May 16. J Clin Neurosci. 2013. PMID: 23685104 Free PMC article.

Publication types

LinkOut - more resources