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. 2006 Feb;4(2):e50.
doi: 10.1371/journal.pbio.0040050. Epub 2006 Feb 14.

Pandemic influenza: the inside story

Affiliations

Pandemic influenza: the inside story

Henry Nicholls. PLoS Biol. 2006 Feb.

Abstract

Recent developments in the molecular genetics of influenza provides clues into how avian flu - H5N1 - could find a way to jump easily from human to human and cause a pandemic

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Conflict of interest statement

The author has declared that he has no competing interests.

Figures

Figure 1
Figure 1. Influenza A Virus
(Image: CDC/F. A. Murphy)
Figure 2
Figure 2. Transmission Electron Micrograph of Avian Influenza A H5N1 Viruses (Gold)
(Image: C. Goldsmith, Public Health Image Library [CDC])
Figure 4
Figure 4. Lung from Influenza Victim Similar to That Used to Extract RNA from the 1918 Killer Strain
(Image: courtesy of the National Museum of Health and Medicine, Armed Forces Institute of Pathology, Washington, D.C., United States.)
Figure 5
Figure 5. The Mechanics of Reverse Genetics
(Image: courtesy of US National Institute of Allergy and Infectious Diseases.)
Figure 3
Figure 3. The Spanish Influenza
(A) Chart showing mortality from the 1918 influenza pandemic in the US and Europe. (B) Emergency military hospital during influenza epidemic, Camp Funston, Kansas, United States. (Image: courtesy of the National Museum of Health and Medicine, Armed Forces Institute of Pathology, Washington, D.C., United States.)

References

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    1. Taubenberger JK, Reid AH, Krafft AE, Bijwaard KE, Fanning TG. Initial genetic characterization of the 1918 “Spanish” influenza virus. Science. 1997;275:1793–1796. - PubMed

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