Review
[The mechanism of bone resorption in chronic inflammation of periodontal disease]
[Article in
Japanese]
Affiliations
- PMID: 16465025
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Review
[The mechanism of bone resorption in chronic inflammation of periodontal disease]
[Article in
Japanese]
Clin Calcium.
2006 Feb.
Abstract
Periodontal disease is caused by infections with oral periodontitis-associated microorganisms. Virulence factors like lipopolysaccharide (LPS) from those microorganisms initiate host immune response and gingival chronic inflammation. As a result, elevated receptor activator of NF-kappaB ligand (RANKL) expression stimulates alveolar bone resorption followed by loss of teeth.
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