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. 2006 Feb;27(2):185-7.
doi: 10.1086/500625. Epub 2006 Feb 8.

Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA

Ana Maria Sandri  1 , Micheline Gisele Dalarosa, Luciana Ruschel de Alcantara, Laura da Silva Elias, Alexandre Prehn Zavascki
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Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA

Ana Maria Sandri et al. Infect Control Hosp Epidemiol. 2006 Feb.

Abstract

After the introduction of routine treatment for every nasal carrier of methicillin-resistant Staphylococcus aureus, active follow-up surveillance for nosocomial methicillin-resistant S. aureus infection was conducted for 5 years in an intensive care unit of a tertiary-care teaching hospital. There was a significant decrease in the incidence of nosocomial methicillin-resistant S. aureus infection during the later years of follow-up. Decolonization of nasal carriers of methicillin-resistant S. aureus is probably associated with such findings.

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