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. 2006 Mar;97(3):509-12.
doi: 10.1111/j.1464-410X.2006.05965.x.

Immediate administration of intravesical mitomycin C after tumour resection for superficial bladder cancer

A Hugh Mostafid  1 , Raj G N Rajkumar, Alistair B Stewart, Raj Singh
Affiliations

Immediate administration of intravesical mitomycin C after tumour resection for superficial bladder cancer

A Hugh Mostafid et al. BJU Int. 2006 Mar.

Abstract

Objective: To assess the feasibility and safety of administering intravesical mitomycin C in theatre immediately after transurethral resection of bladder tumour (TURBT).

Patients and methods: A protocol was developed to allow the safe administration of mitomycin C in theatre immediately after TURBT. Over a 32-month period all patients not excluded by the protocol were given mitomycin C in theatre after TURBT, and any adverse events reported.

Results: In all, 177 instillations were carried out; there were two minor patient-related complications, and no staff-related adverse events.

Conclusion: The immediate administration of mitomycin C in theatre after TURBT is feasible and safe for patients and staff. It provides the earliest and surest prophylaxis against tumour cell re-implantation at TURBT.

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