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Comment
. 2006 Feb;24(2):129-31.
doi: 10.1016/j.immuni.2006.01.011.

An unexpected connection: lymph node lymphangiogenesis and dendritic cell migration

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An unexpected connection: lymph node lymphangiogenesis and dendritic cell migration

Cornelia Halin et al. Immunity. 2006 Feb.
Free article

Abstract

Migration of antigen-presenting dendritic cells (DCs) through lymphatics to draining lymph nodes (LNs) represents a key step in the initiation of an adaptive immune response. In this issue of Immunity, provide the first evidence that remodeling of the lymphatic network within LNs and in peripheral tissues enhances DC migration after immunization and that this process depends on the presence of B cells within the LN.

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