Slipping the barrier: how variants in CARD15 could alter permeability of the intestinal wall and population health
- PMID: 16474103
- PMCID: PMC1856076
- DOI: 10.1136/gut.2005.076075
Slipping the barrier: how variants in CARD15 could alter permeability of the intestinal wall and population health
Abstract
The increased intestinal permeability in Crohn's disease is associated with the presence of variants in the CARD15 gene that are regarded as causative for Crohn's disease, suggesting a genetic rather than an environmental background for intestinal barrier dysfunction in Crohn's disease
Comment on
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Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?Gut. 2006 Mar;55(3):342-7. doi: 10.1136/gut.2005.065557. Epub 2005 Jul 6. Gut. 2006. PMID: 16000642 Free PMC article.
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