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. 1991 Jul;164(1):170-1.
doi: 10.1093/infdis/164.1.170.

Evaluation of the effect of drugs on the cyst form of Toxoplasma gondii

J Huskinson-Mark  1 , F G Araujo, J S Remington
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Evaluation of the effect of drugs on the cyst form of Toxoplasma gondii

J Huskinson-Mark et al. J Infect Dis. 1991 Jul.

Abstract

The cyst form of Toxoplasma gondii has been implicated as a cause of recrudescence of the latent infection in congenitally infected patients and in the immunocompromised host. A method was developed to evaluate the effect of drugs on the cyst form of the parasite and used to evaluate a variety of therapeutic agents. The most active compounds against the cyst form in vitro were arprinocid-N-oxide, azithromycin, and the hydroxynaphthoquinone 566C80.

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