doi: 10.1007/BF02931422.
Distribution of secreted aspartyl proteinases using a polymerase chain reaction assay with SAP specific primers in Candida albicans isolates
Affiliations
- PMID: 16475500
- DOI: 10.1007/BF02931422
Item in Clipboard
Distribution of secreted aspartyl proteinases using a polymerase chain reaction assay with SAP specific primers in Candida albicans isolates
Folia Microbiol (Praha).
2005.
Abstract
Secreted aspartyl proteinase (Sap) distribution among different C. albicans isolates was determined using SAP-specific primers in polymerase chain reaction (PCR) assay. SAP1, SAP2, and SAP3 were detected in 13 of 40 (32.5%), SAP4 in 38/40 (95%), SAP5 were detected in 30/40 (75%), SAP6 in 23/40 (57.5%) of C. albicans strains isolated from blood cultures. SAP1-SAP3 were detected in 37 of 40 (92.5%), SAP4 were detected in 3/40 (7.5%), SAP5 in 3/40 (7.5%), SAP6 in 5/40 (12.5%) of C. albicans strains isolated from vaginal swab cultures. Sap1, Sap2 and Sap3 isoenzymes were found to be related to the vaginopathic potential of C. albicans; Sap4, Sap5 and Sap6 isoenzymes were found to be correlated with systemic infections.
Similar articles
-
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.Infect Immun. 2003 Jun;71(6):3227-34. doi: 10.1128/IAI.71.6.3227-3234.2003. Infect Immun. 2003. PMID: 12761103 Free PMC article.
-
Expression of Candida albicans secreted aspartyl proteinase in acute vaginal candidiasis.J Huazhong Univ Sci Technolog Med Sci. 2007 Jun;27(3):333-5. doi: 10.1007/s11596-007-0330-8. J Huazhong Univ Sci Technolog Med Sci. 2007. PMID: 17641856
-
Differential expression of Candida albicans secreted aspartyl proteinase and phospholipase B genes in humans correlates with active oral and vaginal infections.J Infect Dis. 2003 Aug 1;188(3):469-79. doi: 10.1086/376536. Epub 2003 Jul 14. J Infect Dis. 2003. PMID: 12870130
-
[What functions do six different genes for secretory proteinases have in Candida albicans?].Mycoses. 1998;41 Suppl 1:47-50. doi: 10.1111/j.1439-0507.1998.tb00583.x. Mycoses. 1998. PMID: 9717386 Review. German.
-
Candida albicans secreted aspartyl proteinases.Curr Top Med Mycol. 1996 Dec;7(1):55-69. Curr Top Med Mycol. 1996. PMID: 9504059 Review.
Cited by
-
Candidiasis--do we need to fight or to tolerate the Candida fungus?Folia Microbiol (Praha). 2007;52(3):297-312. doi: 10.1007/BF02931313. Folia Microbiol (Praha). 2007. PMID: 17702470 Review.
-
Effects of antifungal agents in sap activity of Candida albicans isolates.Mycopathologia. 2010 Feb;169(2):91-8. doi: 10.1007/s11046-009-9232-6. Epub 2009 Aug 15. Mycopathologia. 2010. PMID: 19685156
-
Importance of biofilm in Candida parapsilosis and evaluation of its susceptibility to antifungal agents by colorimetric method.Folia Microbiol (Praha). 2007;52(3):209-14. doi: 10.1007/BF02931300. Folia Microbiol (Praha). 2007. PMID: 17702457
-
Differences in proteolytic activity and gene profiles of fungal strains isolated from the total parenteral nutrition patients.Folia Microbiol (Praha). 2011 Mar;56(2):143-8. doi: 10.1007/s12223-011-0023-3. Epub 2011 Apr 1. Folia Microbiol (Praha). 2011. PMID: 21455781 Free PMC article.
-
Phenotypic and molecular detection of virulence factor genes SAP4 and PLB in Candida albicans isolates from the Western part of India.Med J Armed Forces India. 2022 Jul;78(3):271-276. doi: 10.1016/j.mjafi.2020.03.023. Epub 2020 Jul 10. Med J Armed Forces India. 2022. PMID: 35855708 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Miscellaneous