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. 2006 Feb;16(1):61-5.
doi: 10.1007/s10286-006-0312-0.

The effects of exercise training on myocardial adrenergic and muscarinic receptors

Julie Barbier  1 , Sylvia Reland, Nathalie Ville, Françoise Rannou-Bekono, Sara Wong, François Carré
Affiliations

The effects of exercise training on myocardial adrenergic and muscarinic receptors

Julie Barbier et al. Clin Auton Res. 2006 Feb.

Abstract

We investigated the effects of exercise training on heart rate variability (HRV) and myocardial adrenergic and muscarinic receptors in rats. Exercise training induced a decrease in body mass while ventricular size remained unchanged, a development we considered as a relative cardiac hypertrophy. In addition, there was a reduction in the density of myocardial beta(1)-adrenergic receptors. These structural changes were associated with functional adaptations, as illustrated by the increased response of the sinus node to sympathetic blockade.

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