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. 2006 Feb 22;128(7):2156-7.
doi: 10.1021/ja053816e.

Hydrophobic and hydrophilic yoctowells as receptors in water

Sidhanath Bhosale  1 , Sheshanath Bhosale, Tianyu Wang, Marta Kopaczynska, Jurgen-Hinrich Fuhrhop
Affiliations

Hydrophobic and hydrophilic yoctowells as receptors in water

Sidhanath Bhosale et al. J Am Chem Soc. .

Abstract

Hydrophilic yoctowells (volume = 10-24 L) with OEG walls are introduced, which entrap tobramycin, a tetraamino trisaccharide, in water with a binding constant of 107 M-1 but do not interact with cellobiose. This is in contrast to corresponding hydrophobic yoctowells, which kinetically immobilize cellobiose in water, but do not entrap tobramycin.

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