Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Feb;36(2):111-4.
doi: 10.1016/j.medmal.2005.11.012. Epub 2006 Feb 15.

[Efficacy and tolerance of antiretroviral therapy in HIV-2 infected patients in Dakar: preliminary study]

[Article in French]
C T Ndour  1 , G Batista, N M Manga, N F Ngom Guèye, N M Dia Badiane, L Fortez, P S Sow
Affiliations

[Efficacy and tolerance of antiretroviral therapy in HIV-2 infected patients in Dakar: preliminary study]

[Article in French]
C T Ndour et al. Med Mal Infect. 2006 Feb.

Abstract

Objective: The authors had for aim to evaluate the clinical and immunological response as well as the tolerance to antiretroviral therapy in HIV-2 infected patients.

Design: A retrospective chart review was made from August 1998 to August 2004.

Results: 188 patients were on protease inhibitor based regimen. 153 (81.38%) were HIV-1 and 35 (18.62%) HIV-2 infected patients. The mean weight gain was significantly higher in the HIV-2 group at months 9 and 12 (P=0.02 et P=0.01 respectively), whereas CD4 cells count gain was higher in the HIV-1 group at month 6 (P=0.004). New AIDS defining criteria are less likely to occur in HIV-2 infected patients on HAART than in HIV-1 (P=0.004). Lipodystrophy syndrome was present only in HIV-1 infected patients.

Conclusion: Antiretroviral therapy in HIV-2 infected patients shows similar clinical and immunological efficacy than in HIV-1 infected ones and is also well tolerated.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources