Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Jun;17(3):157-71.
doi: 10.1016/j.cytogfr.2006.01.001. Epub 2006 Feb 14.

Roles of activin in tissue repair, fibrosis, and inflammatory disease

Sabine Werner  1 , Christian Alzheimer
Affiliations
Review

Roles of activin in tissue repair, fibrosis, and inflammatory disease

Sabine Werner et al. Cytokine Growth Factor Rev. 2006 Jun.

Abstract

Activins are transforming growth factor beta superfamily members, which were originally identified as inducers of follicle-stimulating hormone release from the pituitary. In recent years, however, additional functions of activins have been discovered, including a role in the morphogenesis of various tissues and organs. In addition, they have been identified as novel players in inflammation and repair, and are most likely involved in the pathogenesis of inflammatory and fibrotic human diseases. In this review we highlight recent data regarding the expression and function of activins in tissue repair, fibrosis, and inflammation.

PubMed Disclaimer

Publication types

LinkOut - more resources