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Comment
. 2006 Mar;126(3):545-7.
doi: 10.1038/sj.jid.5700132.

Looking for the target cell of Kaposi's sarcoma-associated herpesvirus

Nicolas Dupin  1 , Philippe A Grange
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Free article
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Looking for the target cell of Kaposi's sarcoma-associated herpesvirus

Nicolas Dupin et al. J Invest Dermatol. 2006 Mar.
Free article

Abstract

The level of Kaposi's sarcoma-associated herpesvirus (KSHV) cellular viremia in patients with Kaposi's sarcoma could be related to both the tumor burden and its progression. The origin of the spindle cell, the hallmark cell of Kaposi's sarcoma, is still debated. Two hypotheses may be formulated, favoring a lymphatic endothelial cell or an endothelial-cell precursor evolving into a lymphatic phenotype, both preferentially targeted by KSHV.

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