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Review
. 2006 Apr;6(2):184-9.
doi: 10.1016/j.coph.2006.01.003. Epub 2006 Feb 17.

Novel applications of recombinant erythropoietin

Edward J Sharples  1 , Christoph Thiemermann, Magdi M Yaqoob
Affiliations
Review

Novel applications of recombinant erythropoietin

Edward J Sharples et al. Curr Opin Pharmacol. 2006 Apr.

Abstract

Recombinant erythropoietin (EPO) was introduced into clinical practice after the identification of EPO as the major haemopoietic growth factor determining survival and maturation of erythroid precursors. Advances in our understanding of the novel sites of action of EPO in the vasculature, brain, heart and kidney have opened new avenues of therapeutic potential for EPO, and have led to an increased understanding of the biological roles of EPO and its mechanisms of cell protection.

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