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Clinical Trial
. 2006 Feb;27(2):289-92.

HydroCoil for Endovascular Aneurysm Occlusion (HEAL) study: periprocedural results

H J Cloft  1
Affiliations
Clinical Trial

HydroCoil for Endovascular Aneurysm Occlusion (HEAL) study: periprocedural results

H J Cloft. AJNR Am J Neuroradiol. 2006 Feb.

Abstract

Background and purpose: The HydroCoil Embolic System (HES) was developed to improve the efficacy of endovascular treatment of cerebral aneurysms. The purpose of this study is to study the periprocedural results in patients with cerebral aneurysms treated with HES.

Methods: We report the initial periprocedural results in 191 cerebral aneurysms treated with HES in the HydroCoil for Endovascular Aneurysm Occlusion, or HEAL, study. Initial aneurysm occlusion and periprocedural complication rates were evaluated and compared with historical control data regarding aneurysms treated with platinum coils.

Results: An initial occlusion result of "complete" or "near-complete" was achieved in 91.8% of aneurysms. Periprocedural thromboembolic events occurred in 8.1% of aneurysms treated with neurologic deficits related to thromboemboli occurring in 2.1% of aneurysms treated. Intraprocedural aneurysm perforations occurred in 2.8% of previously ruptured aneurysms, and in 0% of previously unruptured aneurysms.

Conclusion: The initial occlusion success and complication rate when HES is used to treat cerebral aneurysms is not significantly different from platinum coils. Follow-up angiography is currently being collected and will be evaluated to determine if use of the HES reduces the rate of aneurysm recurrence.

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Figures

Fig 1.
Fig 1.
Hybrid hydrogel-platinum coil device. Left, Bare platinum coil. Middle, Prehydration image shows initial profile of the device. Highly compact hydrogel material is wrapped around a platinum coil. An outer “overcoil” is wrapped around the hydrogel-covered coil. The outer diameter of the coil is 0.008 inch. The thickness of the hydrogel is approximately 0.0005 inch, such that the outer diameter of the gel covering is 0.009 inch. With the “overcoil,” the outer diameter is 0.013 inch. Right, Posthydration image of the device shows marked expansion of the hydrogel material, which has become translucent. The radial thickness of the expanded hydrogel is approximately 0.009 inch, such that the total outer diameter of the hydrated device is 0.027 inch.
Fig 2.
Fig 2.
Scatter graph of packing attenuation versus aneurysm diameter in aneurysms treated with HydroCoil Embolic System in the HEAL registry.
See this image and copyright information in PMC

Comment in

References

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