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. 1991 Jul 15;47(7):731-4.
doi: 10.1007/BF01958829.

Activity of soluble factors produced by Epstein-Barr virus-transformed human B lymphocytes on different cell lines

C Garzelli  1 , A Bazzichi
Affiliations

Activity of soluble factors produced by Epstein-Barr virus-transformed human B lymphocytes on different cell lines

C Garzelli et al. Experientia. .

Abstract

Self-stimulatory growth factors, produced by a human Epstein-Barr virus (EBV)-positive lymphoblastoid B cell line, named BA-D10-4, have been tested for the capacity to induce DNA synthesis in various human and animal cell lines, including lymphoid, either EBV-positive or EBV-negative, and non-lymphoid cell lines. It has been found that BA-D10-4 cells produce growth factors which seem to be essential for their sustained proliferation in vitro, and which increase DNA synthesis in different primate lymphoid cells, independently of the presence of the EBV genome and of the lymphocyte lineage.

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References

    1. Proc Natl Acad Sci U S A. 1987 May;84(10):3452-6 - PubMed
    1. Cancer Res. 1983 Oct;43(10):4562-8 - PubMed
    1. J Immunol. 1987 Apr 15;138(8):2527-34 - PubMed
    1. N Engl J Med. 1986 Apr 3;314(14):874-9 - PubMed
    1. Immunology. 1990 May;70(1):100-5 - PubMed

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