Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Apr;6(2):125-9.
doi: 10.1016/j.coph.2005.10.007. Epub 2006 Feb 17.

Hydrogen sulphide--a novel mediator of inflammation?

Ling Li  1 , Madhav Bhatia, Philip K Moore
Affiliations
Review

Hydrogen sulphide--a novel mediator of inflammation?

Ling Li et al. Curr Opin Pharmacol. 2006 Apr.

Abstract

Hydrogen sulphide (H2S) is a naturally occurring gas synthesized from cysteine. It exhibits vasodilator activity (most probably by opening vascular smooth muscle K(ATP) channels), influences leucocyte chemotaxis and promotes vascular smooth muscle cell apoptosis. Increased biosynthesis of H2S has been demonstrated in animal models of septic/endotoxic and haemorrhagic shock, pancreatitis and carrageenan-evoked hindpaw oedema in the rat. In each case, pharmacological inhibition of H2S biosynthesis is anti-inflammatory.

PubMed Disclaimer

Publication types

LinkOut - more resources