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. 2006 May;127(5):494-6.
doi: 10.1016/j.mad.2006.01.002. Epub 2006 Feb 20.

Limits to deficit accumulation in elderly people

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Limits to deficit accumulation in elderly people

Kenneth Rockwood et al. Mech Ageing Dev. 2006 May.

Abstract

We evaluated limits to the accumulation of deficits (symptoms, diseases, disabilities) for 33,069 people aged 65+ years. We combined deficits in a frailty index (theoretical range 0-1) and found that the 99% limit varied little between samples, representing a frailty index value of about 0.65 +/- 0.05. This near-maximum shows no relationship with age. It is the same in community and institutional samples, even though the mean value is much higher in the latter. The data suggest a level of frailty beyond which, even in developed countries, further deficit accumulation is not sustainable.

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