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Case Reports
. 2006 Mar;81(3):1109-11.
doi: 10.1016/j.athoracsur.2004.12.030.

Arteriolar blood flow pulsatility in a patient before and after implantation of an axial flow pump

Helmut Habazettl  1 , Marian Kukucka, Yu G Weng, Wolfgang M Kuebler, Roland Hetzer, Hermann Kuppe, Axel R Pries
Affiliations
Case Reports

Arteriolar blood flow pulsatility in a patient before and after implantation of an axial flow pump

Helmut Habazettl et al. Ann Thorac Surg. 2006 Mar.

Abstract

In a patient with end stage ischemic heart failure scheduled for implantation of an axial flow pump small arteriolar flow pattern was recorded using a novel intravital microscope. Preoperative arteriolar blood flow velocity was highly pulsatile, ranging from about 7 to 16 mm per second in a 12.8 microm diameter arteriole. After implantation of the pump, this pulsatility was abrogated and arteriolar blood flow velocity changed instantaneously with changes in pump speed (eg, 2 mm/s at 5,000 rpm vs 3.5 mm/s at 8,000 rpm in an 8.9 microm diameter arteriole). This lack of flow velocity oscillations may have profound long-term effects on shear stress regulated arteriolar remodeling.

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