Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2006 Mar 4;332(7540):511-7.
doi: 10.1136/bmj.38743.421574.7C. Epub 2006 Feb 17.

Opportunistic screening for alcohol use disorders in primary care: comparative study

Simon Coulton  1 , Colin Drummond, Darren James, Christine Godfrey, J Martin Bland, Steve Parrott, Timothy Peters; Stepwice Research Team
Affiliations
Comparative Study

Opportunistic screening for alcohol use disorders in primary care: comparative study

Simon Coulton et al. BMJ. .

Abstract

Objective: To evaluate the efficacy and relative costs of different screening methods for the identification of alcohol use disorders in an opportunistic screening programme in primary care in the United Kingdom.

Design: Comparative study.

Setting: Six general practices in south Wales.

Participants: 194 male primary care attendees aged 18 or over who completed an alcohol use disorders identification test (AUDIT) questionnaire.

Main outcome measures: Scores on alcohol use disorders identification test and measures of gamma-glutamyltransferase, aspartate aminotransferase, per cent carbohydrate deficient transferrin, and erythrocyte mean cell volume. Hazardous alcohol consumption, weekly binge consumption, and monthly binge consumption were ascertained using the time line follow back method over the previous 180 days. Alcohol dependence was determined using the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. Unit costs were established from published resource references and from actual costs of analysing the biochemical tests.

Results: A significant correlation was observed be alcohol consumption and score on the alcohol use disorders identification test (Pearson's correlation coefficient r = 0.74) and measures of gamma-glutamyltransferase (r = 0.20) and per cent carbohydrate deficient transferrin (r = 0.36) but not aspartate aminotransferase (r = 0.08) or erythrocyte mean cell volume (r = 0.02). The alcohol use disorders identification test exhibited significantly higher sensitivity, specificity, and positive predictive value than all of the biochemical markers for hazardous consumption (69%, 98%, and 95%), weekly binge consumption (75%, 90%, and 71%), monthly binge consumption (66%, 97%, and 91%), and alcohol dependence (84%, 83%, and 41%). The questionnaire was also more cost efficient, with a lower cost per true positive for all consumption outcomes.

Conclusion: The alcohol use disorders identification test questionnaire is an efficient and cost efficient diagnostic tool for routine screening for alcohol use disorders in primary care.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Receiver operating characteristic curve indicating screening properties of alcohol use disorders identification test, γ-glutamyltransferase, aspartate aminotransferase, per cent carbohydrate deficient transferrin, and erythrocyte mean cell volume for hazardous alcohol consumption, monthly binge consumption, weekly binge consumption, and alcohol dependence in 194 male attendees in primary care
See this image and copyright information in PMC

Comment in

References

    1. Prime Minister's Strategy Unit. Alcohol harm reduction strategy for England. London: Stationery Office, 2004.
    1. Royal College of Physicians. Alcohol—can the NHS afford it? London: RCP, 2003.
    1. Maynard A, Godfrey C. Alcohol policy: evaluating the options. Br Med Bull 1994;50: 221-30. - PubMed
    1. Allen J, Reinert D, Volk R. The alcohol use disorders identification test: an aid to recognition of alcohol problems in primary care patients. Prev Med 2001;33: 428-33. - PubMed
    1. Kaner E, Heather N, McAvoy B, Lock C, Gilvarry E. Interventions for excessive alcohol consumption in primary health care: attitudes and practices of English general practitioners. Alcohol Alcohol 1999;34: 559-66. - PubMed