Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1991;118(3-4):269-77.
doi: 10.1007/BF01314037.

Comparison of human and porcine group C rotaviruses by northern blot hybridization analysis

Affiliations
Comparative Study

Comparison of human and porcine group C rotaviruses by northern blot hybridization analysis

Y Qian et al. Arch Virol. 1991.

Abstract

The genetic relationship between human and porcine Gp C rotaviruses and between Gp C and Gp A or B rotaviruses was examined by Northern blot hybridization. Cross-hybridization studies using radiolabeled ssRNA transcript probes demonstrated that the human and porcine Gp C rotaviruses shared a high degree of nucleotide sequence homology in most of the eleven gene segments; the greatest sequence divergence was observed in gene 7. Neither the human nor the porcine Gp C probe hybridized strongly with gene segments from Gp A reference strains or a Gp B bovine rotavirus. These data indicate that genetically, porcine and human Gp C rotaviruses are closely related, whereas they are quite distinct from Gp A or B suggesting that porcine and human Gp C rotaviruses may have evolved from a common ancestral source.

PubMed Disclaimer

Similar articles

Cited by

References

    1. J Virol. 1982 Aug;43(2):369-78 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Clin Microbiol. 1987 Feb;25(2):295-300 - PubMed
    1. J Virol. 1986 Jan;57(1):183-90 - PubMed
    1. Virology. 1990 Oct;178(2):579-83 - PubMed

Publication types