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. 2006 Feb 15;66(4):1897-9.
doi: 10.1158/0008-5472.CAN-05-3034.

Cancer risk assessment at the atomic level

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Cancer risk assessment at the atomic level

Alvaro N A Monteiro et al. Cancer Res. .

Abstract

A flurry of articles on the structure of different domains of BRCA1 and BRCA2 have not only shed light on the biology of these proteins but have also raised hopes that these data could eventually be used to infer cancer association for a large number of inherited missense mutations whose effect on protein function is unclear.

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