Case Reports
doi: 10.1111/j.1365-2559.1991.tb00864.x.
Extramammary Paget's disease of the vulva with dermal invasion and vulval intra-epithelial neoplasia
Affiliations
- PMID: 1649117
- DOI: 10.1111/j.1365-2559.1991.tb00864.x
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Case Reports
Extramammary Paget's disease of the vulva with dermal invasion and vulval intra-epithelial neoplasia
Histopathology.
1991 Apr.
Abstract
Vulval biopsies from a 66-year-old lady complaining of pruritus showed intraepithelial Paget's disease. On simple vulvectomy, extramammary Paget's disease was found to be associated with vulval intra-epithelial neoplasia (VIN III) and superficial dermal invasive adenocarcinoma. Bilateral inguinal lymphadenectomy later revealed metastatic spread of the tumour. We believe this is a unique combination and discuss the possible origins in relation to this lady's past medical history of breast carcinoma 20 years and spinal metastases 17 years before.
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