[Experimental study of the effects of puerarin on biological characters of osteoblasts in vitro]
- PMID: 16494032
[Experimental study of the effects of puerarin on biological characters of osteoblasts in vitro]
Abstract
Objective: To observe the effect of puerarin on cell proliferation, differentiation, maturation and mineralization in cultured rat osteoblasts.
Method: Osteoblasts from craniums of newly born SD rats were cultured in vitro. MTT, PNPP and ARS were used to observe the proliferation, activity of ALP and the number of mineral node of cultured osteoblasts in vitro.
Result: It was found that puerarin had the effect on stimulating cell proliferation, activity of ALP and the number of mineral node of cultured osteoblasts (P < 0.01 or P < 0.05).
Conclusion: Puerarin can promote proliferation, differentiation, maturation and mineralization of the osteoblasts in vitro.
Similar articles
-
[Experimental study of the effect of Bushen Huoxue recipe on biological characters of osteoblasts in vitro].Zhong Yao Cai. 2005 Sep;28(9):803-5. Zhong Yao Cai. 2005. PMID: 16447875 Chinese.
-
[Effects of soybean isoflavone and calcium on proliferation, differentiation and mineralization of cultured osteoblasts in vitro].Wei Sheng Yan Jiu. 2003 Jul;32(4):361-2, 401. Wei Sheng Yan Jiu. 2003. PMID: 14535101 Chinese.
-
[Biological effect of serum of kidney-tonifying traditional Chinese drug-fed rats on cultured osteoblasts].Di Yi Jun Yi Da Xue Xue Bao. 2004 Nov;24(11):1248-50. Di Yi Jun Yi Da Xue Xue Bao. 2004. PMID: 15567769 Chinese.
-
[Effects of genistein on proliferation and differentiation of cultured osteoblasts in vitro].Zhong Yao Cai. 2002 Nov;25(11):803-5. Zhong Yao Cai. 2002. PMID: 15562707 Chinese.
-
New insights into mineralogenic effects of vanadate.Cell Mol Life Sci. 2009 Dec;66(24):3831-6. doi: 10.1007/s00018-009-0137-9. Epub 2009 Sep 4. Cell Mol Life Sci. 2009. PMID: 19760363 Free PMC article. Review. No abstract available.