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Comparative Study
. 2006 Mar;50(3):1071-4.
doi: 10.1128/AAC.50.3.1071-1074.2006.

Medium plays a role in determining expression of acrB, marA, and soxS in Escherichia coli

Andrew M Bailey  1 , Mark A Webber, Laura J V Piddock
Affiliations
Comparative Study

Medium plays a role in determining expression of acrB, marA, and soxS in Escherichia coli

Andrew M Bailey et al. Antimicrob Agents Chemother. 2006 Mar.

Abstract

Analysis of expression of acrB, marA, and soxS in rich and minimal media, at early and late logarithmic growth phases, showed that acrB had increased expression in minimal medium compared to rich medium, but expression decreased dose dependently upon exposure to ciprofloxacin.

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Figures

FIG. 1.
FIG. 1.
Expression of (A) marA in early logarithmic phase, (B) marA in late logarithmic phase, (C) soxS in early logarithmic phase, (D) soxS in late logarithmic phase, (E) acrB in early logarithmic phase, and (F) acrB in late logarithmic phase. Unfilled bars, rich medium; filled bars, minimal medium; asterisk, significant difference between corresponding rich and minimal medium pairs at the same MIC and growth phase; square, significant difference between the antibiotic-free control and corresponding MIC multiple (rich medium); diamond, significant difference between the antibiotic-free control and corresponding MIC multiple (minimal medium); error bars, standard deviation of the mean of each value. CIP, ciprofloxacin.
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