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. 2006 Feb 24;124(4):677-81.
doi: 10.1016/j.cell.2006.02.005.

The rational design of an AIDS vaccine

Daniel C Douek  1 , Peter D Kwong, Gary J Nabel
Affiliations
Free article

The rational design of an AIDS vaccine

Daniel C Douek et al. Cell. .
Free article

Abstract

The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose significant challenges for vaccine development. AIDS vaccine design requires a scientifically driven, rational approach that encompasses the latest advances in viral molecular genetics, structural biology, and immunology.

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