Review
doi: 10.1016/j.cell.2006.02.012.
Bacterial adhesion and entry into host cells
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- PMID: 16497583
- DOI: 10.1016/j.cell.2006.02.012
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Review
Bacterial adhesion and entry into host cells
Cell.
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Abstract
Successful establishment of infection by bacterial pathogens requires adhesion to host cells, colonization of tissues, and in certain cases, cellular invasion-followed by intracellular multiplication, dissemination to other tissues, or persistence. Bacteria use monomeric adhesins/invasins or highly sophisticated macromolecular machines such as type III secretion systems and retractile type IV pili to establish a complex host/pathogen molecular crosstalk that leads to subversion of cellular functions and establishment of disease.
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