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Comment
. 2006 Mar 2;49(5):645-6.
doi: 10.1016/j.neuron.2006.02.009.

Rookie snail protein LAPS veteran C/EBP: net transcriptional proceeds for long-term facilitation

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Rookie snail protein LAPS veteran C/EBP: net transcriptional proceeds for long-term facilitation

Kristin L Eckel-Mahan et al. Neuron. .
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Abstract

Long-term changes in synaptic plasticity require new protein synthesis. This preview discusses data from Kim et al. (this issues of Neuron) that demonstrate the requirement of a novel, nucleolar protein, LLP (LAPS18-like protein), for the formation of long-term facilitation in Aplysia. LLP binds to and transcriptionally activates C/EBP, thereby promoting the formation of long-term facilitation and behavioral sensitization.

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