The role of surgical resection of liver metastases in colorectal carcinoma
- PMID: 1650502
The role of surgical resection of liver metastases in colorectal carcinoma
Abstract
While hepatic resection of colorectal carcinoma, metastatic to the liver, is a suitable and effective treatment, it nevertheless remains applicable only to a highly selective group of patients. Even within this highly selective group of patients only a minority will survive 5 years disease-free indicating the increased sophistication needed to understand the biological factors that control outcome. It is clear that the good results come from biological suitability and not temporal acceleration of the detection process. Appropriate patients after careful selection and sophisticated diagnostic studies should be subjected to exploration and attempted hepatic resection. A preliminary prognostic scoring system has been presented to illustrate the usefulness of this approach.
Similar articles
-
Technical and biological factors in disease-free survival after hepatic resection for colorectal cancer metastases.Arch Surg. 1992 May;127(5):561-8; discussion 568-9. doi: 10.1001/archsurg.1992.01420050085011. Arch Surg. 1992. PMID: 1575626
-
Prognostic factors for poor survival after repeat hepatectomy in patients with colorectal liver metastases.Surgery. 2003 Jun;133(6):627-34. doi: 10.1067/msy.2003.151. Surgery. 2003. PMID: 12796730
-
Importance of the Postoperative Carcinoembryonic Antigen Level during Follow-Up after Curative Resection in Patients with Liver Metastatic Colorectal Carcinoma.Hepatogastroenterology. 2014 Jun;61(132):989-93. Hepatogastroenterology. 2014. PMID: 26158154
-
[Surgical treatment for colorectal liver metastases--results of multi-institute study for effects of radical hepatectomy].Gan To Kagaku Ryoho. 2004 May;31(5):690-4. Gan To Kagaku Ryoho. 2004. PMID: 15170974 Review. Japanese.
-
[Surgical treatment of liver metastases from colorectal cancer patient selection and oncological outcome].Nihon Geka Gakkai Zasshi. 2001 May;102(5):385-9. Nihon Geka Gakkai Zasshi. 2001. PMID: 11394001 Review. Japanese.
Cited by
-
Laparoscopic radiofrequency ablation of hepatic tumors: prospective clinical evaluation of ablation size comparing two treatment algorithms.Surg Endosc. 2004 Mar;18(3):390-6. doi: 10.1007/s00464-003-8911-5. Epub 2004 Jan 23. Surg Endosc. 2004. PMID: 14735342
-
Angiogenesis inhibitor TNP-470 suppresses growth of peritoneal disseminating foci of human colon cancer line Lovo.World J Gastroenterol. 2002 Oct;8(5):853-6. doi: 10.3748/wjg.v8.i5.853. World J Gastroenterol. 2002. PMID: 12378629 Free PMC article.
-
Isolated hepatic perfusion in the pig with TNF-alpha with and without melphalan.Br J Cancer. 1997;75(10):1447-53. doi: 10.1038/bjc.1997.248. Br J Cancer. 1997. PMID: 9166936 Free PMC article.
-
Effect of angiogenesis inhibitor SU6668 in combination with 5-Fu on liver metastasis from transplantation tumors of human colorectal cancer in nude mice.Int J Clin Exp Med. 2014 Oct 15;7(10):3578-82. eCollection 2014. Int J Clin Exp Med. 2014. PMID: 25419401 Free PMC article.
-
Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population.Mol Med Rep. 2016 Sep;14(3):2541-7. doi: 10.3892/mmr.2016.5536. Epub 2016 Jul 21. Mol Med Rep. 2016. PMID: 27485384 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical