[A seroepidemiological survey of neutralization antibodies to polioviruses in Linqu and Yucheng counties of Shandong Province, China]

Abstract

Two hundred and fifty two serum samples from Linqu county and 249 serum samples from Yucheng county, in Shandong province, China, were collected among the age group of 0-, 1-, 2-, 3- and 5-9 years old and assayed by microneutralization test in 1989. The results showed that the positive rates (PRs) and geometric mean titres (GMTs) of antibodies to poliovirus type 1-3 in Linqu county were 82.54%, 80.56%, 82.94% and 27.06, 22.94, 24.24, respectively, and much significantly higher than those, in Yucheng county (84.34%, 51.81%, 59.04% and 16.78, 2.79, 3.40) except the PR to typel.for children in both countries, the PRs and GMTs were highest in the age group of 2-4 years old, and no significant difference was found between male and female. All above indicated that EPI was helpful for improving immune status of children, the coverage of TOPV and quality of vaccination should still be emphasized in future EPI works.