[The relation of lectin receptor's activity of hepatocellular carcinoma (HCC) with the recurrence after curative hepatectomy]

Abstract

Recurrence is an important factor affecting the survival rate of patients with hepatocellular carcinoma (HCC) after curative hepatectomy. Twelve types of lectin receptors in 33 cases of HCC tissues were determined by avidin-biotin-peroxidase complex (ABC) method. The relationship between lectin receptors, HCC grading and recurrence time after curative hepatectomy was investigated. The results showed that tumor-free period of patients after the resection of HCC was not closely related to the size of resected tumors, their pathological gradings as well as most lectin receptors. However, tumors that recurred longer than two years after curative hepatectomy had Bandeiraea simplifolia agglutinin I (BSAI) receptors obviously fewer than those recurring within two years. It is suggested that BSAI receptors in tumor tissues might be a useful index in the prognosis of HCC patients after hepatectomy.