Genome-wide approaches to identifying genetic factors in host susceptibility to tuberculosis
- PMID: 16513396
- DOI: 10.1016/j.micinf.2005.10.025
Genome-wide approaches to identifying genetic factors in host susceptibility to tuberculosis
Abstract
Host genetic factors are important in determining susceptibility to Mycobacterium tuberculosis. Genome-wide linkage studies have been performed in humans and in murine models of tuberculosis susceptibility. These studies have identified several important candidate loci for susceptibility to tuberculosis. This is an important step in resolving the complex etiology of the disease.
Comment in
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Introduction: new susceptibility genes in mycobacterial infectious diseases.Microbes Infect. 2006 Apr;8(4):1117-8. doi: 10.1016/j.micinf.2005.10.026. Epub 2006 Jan 19. Microbes Infect. 2006. PMID: 16517199 No abstract available.
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