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. 2006 Mar 21;20(5):780-2.
doi: 10.1097/01.aids.0000216383.14808.13.

Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

Luiz C J Alcantara  1 , Tulio de Oliveira, Michelle Gordon, Oliver Pybus, Rita Elizabeth Mascarenhas, Magda O Seixas, Marilda Gonçalves, Carol Hlela, Sharon Cassol, Bernardo Galvão-Castro
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Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

Luiz C J Alcantara et al. AIDS. .

Abstract

We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu-Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup. The presence of South African sequences in two different clusters from Brazil, and the finding of the beta-globin haplotype in infected hosts are consistent with the transmission of this virus from southern Africa to Brazil.

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