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. 1975 Feb 15;15(2):171-9.
doi: 10.1002/ijc.2910150202.

Transformation of horse skin cells by type-C sarcoma viruses

J S Rhim, H S Ro, E B Kim, R V Gilden, R J Huebner

Transformation of horse skin cells by type-C sarcoma viruses

J S Rhim et al. Int J Cancer. .

Abstract

A horse skin cell line (E. Derm, NBL-6, CCL-57) was susceptible to focus formation by the Kirsten mouse sarcoma virus, feline sarcoma virus (ST stain) and the MSV pseudotypes with woolly monkey, gibbon monkey, RD-114, AT-124, baboon placenta and murine xenotropic (BALB/c 3T3 and C57L/JD) type-C viruses. Foci were detected within 5 days after infection and the transformed cells continued to produce infectious virus and group-specific antigen of their respective type-C leukemia viruses. The transformation efficiency of various type-C sarcoma viruses in horse cells was also very high.

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