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Review
. 2006 Mar;82(965):192-8.
doi: 10.1136/pgmj.2005.038109.

Nutritional support in the premature newborn

J W L Puntis  1
Affiliations
Review

Nutritional support in the premature newborn

J W L Puntis. Postgrad Med J. 2006 Mar.

Abstract

The theory and practice of nutritional support in the premature newborn has assumed increasing importance with survival of greater numbers of very immature infants. After birth, many do not tolerate full enteral feeding until gastrointestinal motor function has matured. During this process some will develop necrotising enterocolitis (NEC), a devastating failure of adaptation to postnatal life that may result in death, or severe complications. The feeding strategy that minimises the risk of NEC remains to be defined. In addition, promoting growth rates and nutrient accretion equivalent to those achieved during fetal development while optimising neurodevelopmental and long term health outcomes represents an important challenge for neonatologists. This review will focus on the problems associated with enteral nutrition, the requirement for parenteral nutrition, and the long term consequences of early nutritional interventions, underlining the need for prolonged follow up in assessing the potential benefits of different approaches to feeding.

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Conflict of interest statement

Conflicts of interest: none declared.

References

    1. Lucas A, Fewtrell M S, Cole T J. Fetal origins of adult disease—the hypothesis revisited. BMJ 1999319245–249. - PMC - PubMed
    1. Aggett P J, Agostoni C, Goulet O.et al The nutritional and safety assessment of breast milk substitutes and other dietary products for infants: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroent Nutr 200132256–258. - PubMed
    1. Aggett P J, Agostoni C, Axellson I.et al Core data for nutrition trials in infants: a discussion document—a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroent Nutr 200336338–342. - PubMed
    1. Kleinman R E. ed. Nutritional needs of preterm infants. In: Pediatric nutrition handbook. 4th ed. Elk Grove Village: American Academy of Pediatrics, 199855–87.
    1. Bisset W M. Intestinal motor activity in the preterm infant. In: Milla PJ, ed. Disorders of gastrointestinal motility in childhood. Chichester: Wiley, 1988